Our worst human flaw could be thinking ourselves righteous, and others villainous. This is why we deny our worst evils, and cannot celebrate our enemies’ greatest good - till they become real friends.
Ideal human conceptions of the perfect, ultimate Almighty are inherently flawed. The standards of logic involved in flawless science are unattainable by the imperfections of flawed human mortals of sapience.
And so sages go insane from the perfect attainment of their unearthly awareness. As for paragons of virtue, beware their coin flip-side of apexes of corruption, not all but few ever revealed in full glory of their deceptions.
And thus you in the hubris of the highest just, humiliate in the final value of your humble bones and organs. You are but on loan to achieve greatness or disgrace in a lifetime, after which you return whatever mantle you drew out. Only in your insignificance will you perhaps glimpse the supreme greatness of your single distinct life.